Peptide Stacking Data
Stacking peptides can create synergistic effects or amplify side effects. Below are common stacks, their rationale, and community-reported outcomes.
Popular Peptide Stacks
Stack Name | Peptides | Synergy Rationale | Monthly Cost | Effectiveness Rating |
---|---|---|---|---|
Classic GH Stack | CJC-1295 No DAC (100mcg) + Ipamorelin (200mcg), 2x daily | GHRH + GHRP = amplified GH pulse; complementary mechanisms | $71-113 | 9/10 - Gold standard for GH release |
Healing Stack | BPC-157 (500mcg 2x/day) + TB-500 (5mg 2x/week) | BPC for localized healing, TB-500 for systemic tissue repair | $212-303 | 7/10 - Expensive but reported synergy for injuries |
Budget GH Stack | GHRP-2 (100mcg) + CJC-1295 (100mcg), 3x daily | Same mechanism as Ipa/CJC but cheaper; more hunger side effect | $54-81 | 8/10 - Great value if hunger tolerable |
Recovery + GH | CJC/Ipa stack + BPC-157 (250mcg 2x/day) | GH for overall recovery, BPC for injury-specific healing | $155-248 | 8/10 - Popular with athletes |
Skin/Anti-Aging | CJC/Ipa (standard) + GHK-Cu topical (2% serum) | Systemic GH benefits + topical skin improvement | $95-161 | 6/10 - Subjective results |
Fat Loss Focus | Tesamorelin (1mg daily) + Ipamorelin (300mcg 2x/day) | Tesamorelin for visceral fat, Ipa for general GH boost | $158-264 | 8/10 - Best for targeted fat loss |
Gut + Immune | BPC-157 (500mcg oral 2x/day) + LL-37 (2mg 3x/week) | BPC for gut lining, LL-37 for immune/antimicrobial | $228-375 | 5/10 - Limited data, expensive |
Synergy vs Redundancy Matrix
Combination | Interaction | Result | Recommendation |
---|---|---|---|
CJC-1295 + Ipamorelin | Synergistic | Amplified GH release (3-5x vs either alone) | Stack - Gold standard |
CJC-1295 + GHRP-2 or GHRP-6 | Synergistic | Similar to Ipa but cheaper; more hunger | Stack - Budget option |
BPC-157 + TB-500 | Complementary | Different healing mechanisms; work together | Stack - For severe injuries |
Ipamorelin + GHRP-2 | Redundant | Both GHRP agonists; no added benefit | Don't stack - Pick one |
CJC-DAC + CJC-NoDAC | Redundant | Same peptide, different half-lives; confusing | Don't stack - Pick one |
Tesamorelin + CJC/Ipa | Overlapping | All increase GH; may be overkill + $$$ | Questionable - Expensive redundancy |
Any GH peptide + BPC-157 | Complementary | Different mechanisms; GH for general recovery, BPC for specific healing | Stack works - Common combo |
BPC-157 + GHK-Cu (both injectable) | Overlapping (healing) | Both promote healing; may be redundant unless targeting different tissues | Questionable - Try one first |
GH peptides + GHK-Cu topical | Complementary | Systemic vs topical; different benefits | Stack OK - No conflict |
Multiple GHRPs (Ipa + GHRP-2 + GHRP-6) | Redundant + risky | Amplified side effects, minimal added GH release | Don't stack - Overkill |
Timing & Administration for Common Stacks
Stack | Timing Protocol | Food Restrictions | Notes |
---|---|---|---|
CJC/Ipamorelin | Morning (fasted), Pre-bed. Optional: Post-workout | Must be fasted 2+ hrs; wait 20+ min before eating | Inject both together in same session; can mix in same syringe |
BPC-157 + TB-500 | BPC 2x daily anytime; TB-500 2x/week anytime | None | BPC can be near injury site; TB-500 anywhere subQ |
CJC/Ipa + BPC-157 | GH peptides fasted; BPC anytime (can dose together) | GH peptides fasted only | Can inject BPC at same time as GH peptides (separate sites) |
Tesamorelin + Ipamorelin | Tesamorelin bedtime; Ipamorelin morning + bedtime | Ipa must be fasted | Can inject together at bedtime dose |
GHRP-2 + CJC | 3x daily: Morning, post-workout (or afternoon), bedtime | All doses fasted (critical for GH release) | Hunger from GHRP-2 can be timed with meals (dose, wait 20 min, eat) |
Stacking Side Effect Amplification
Stack | Amplified Side Effects | Mitigation |
---|---|---|
CJC/Ipa (or any GH stack) | Water retention, carpal tunnel symptoms | Reduce sodium, stay hydrated, lower dose if severe |
Multiple GH peptides (e.g., CJC/Ipa + Tesamorelin) | Insulin resistance risk increases | Monitor glucose closely; not recommended long-term |
BPC-157 + TB-500 | Lethargy (from TB-500) | TB-500 causes this alone; BPC doesn't amplify it significantly |
GHRP-2 or GHRP-6 + anything | Hunger (from GHRP), may make dieting hard | Time doses before planned meals; switch to Ipa if intolerable |
GH peptides + GHK-Cu injectable | None reported consistently | Generally well-tolerated combination |
Advanced Stacks (Experienced Users Only)
Stack | Components | Goal | Complexity | Monthly Cost |
---|---|---|---|---|
Full GH/Healing | CJC/Ipa + BPC-157 + TB-500 + GHK-Cu | Maximum recovery from injury/surgery | High (6+ injections/day) | $320-520 |
Body Recomp Aggressive | Tesamorelin + GHRP-2 + CJC + BPC-157 | Fat loss + healing + recovery | High (multiple daily doses) | $260-450 |
Longevity Protocol | CJC/Ipa + GHK-Cu (injectable) + Thymosin Alpha-1 | Anti-aging, immune support, general health | Moderate | $240-380 |
Gut Health Max | BPC-157 oral + LL-37 + Thymosin Alpha-1 | Gut lining + immune + antimicrobial | Moderate | $348-575 |
Stacking Mistakes to Avoid
- Stacking multiple new peptides at once: Can't identify which causes side effects or benefits
- Redundant GHRP stacking: Ipa + GHRP-2 + GHRP-6 = wasted money, not more GH
- Ignoring total injection frequency: 6+ injections/day often unsustainable
- Not cycling GH peptides: Even when stacked, cycle 8-12 weeks on, 4 weeks off
- Mixing peptides in same vial: Reconstitute separately; can draw both into one syringe but don't store mixed
- Stacking without clear goal: "More is better" rarely applies; have specific outcome in mind
- Forgetting cost adds up: $100/month peptide + $150/month stack = $250; budget accordingly
Progressive Stacking Approach
Phase | What to Run | Duration | Purpose |
---|---|---|---|
Phase 1: Baseline | Single peptide (e.g., Ipamorelin only or BPC-157 only) | 4-6 weeks | Assess individual response, tolerance, effectiveness |
Phase 2: Basic Stack | Add complementary peptide (e.g., add CJC to Ipa) | 8-12 weeks | Evaluate synergy; if good results, continue |
Phase 3: Optimization | Fine-tune doses, timing; possibly add third peptide if clear need | 8-12 weeks | Maximize results while managing sides/cost |
Phase 4: Cycle Off | All GH peptides stopped; can continue BPC/healing peptides if needed | 4-6 weeks minimum | Prevent desensitization; assess if benefits persist |
Community-Reported Stack Effectiveness
Stack | % Reporting "Better than Single Peptide" | Common Feedback |
---|---|---|
CJC + Ipamorelin | 78% | "Clear synergy; worth stacking" |
BPC-157 + TB-500 | 68% | "Faster healing but expensive; BPC alone often enough" |
CJC/Ipa + BPC | 71% | "Recovery and healing covered; popular with athletes" |
Tesamorelin + Ipamorelin | 61% | "Works but pricey; Tesa alone often sufficient" |
GH peptides + GHK-Cu | 52% | "Unclear if GHK adds much; results subtle" |